He was a member of the Edo State House of Assembly representing Ikpoba-Okha State Constituency from 2007- 2015 on two terms. In 2014, he defected from the All Progressives Congress (APC) to the Peoples Democratic Party (PDP).

Ise-Idehen attended Emotan Primary School and was a pioneer student of the University of Benin Demonstration Secondary School, both in Benin City. He excelled in academics and Sports and represented the defunct Bendel State as a shot-putter and Discus thrower in national and international competitions.

A member of the Peoples Democratic Party (PDP) in the House of Representatives (Egor/Ikpoba-Okha Federal Constituency), he won a return ticket at the PDP Primary in May.

Ise-Idehen (born June 7, 1969), married with children,a devout Catholic, philanthropist, a Knight of Columbus died on Friday morning from yet undisclosed ailment.