De Bruyne was substituted and spent the last 25 minutes of Wednesday’s bad-tempered 0-0 draw with Atletico Madrid in Spain with ice packed around his right ankle after a kick from Felipe.

Meanwhile, Walker limped off in the 73rd minute of the Champions League quarter-final second-leg tie after rolling his left ankle and was pictured wearing a protective boot on Thursday.

De Bruyne required stitches to his wound after the game against Atletico and neither he nor Walker were able to train on Friday.

“They didn’t train today,” City boss Pep Guardiola said on Friday. “We’ll see tomorrow but apparently it’d be so close after what happened on Wednesday.”

Nathan Ake has impressed as a makeshift left-back in recent weeks but could be moved back into the centre against Liverpool, with Oleksandr Zinchenko also available.

 *Liverpool's Team News* 

Although the Reds boss made several changes to his starting lineup for Wednesday’s Champions League draw with Benfica, there were still a couple of concerns to come out of the game.

A knock to Diogo Jota makes him a doubt for Saturday’s trip while Klopp assured fans that Salah came out of his short substitute appearance unscathed.

“About Mo’s knock, I don’t know really. Nobody told me yet. I exchanged with two physios. Nobody told me Mo has a problem. For the moment, everybody should be fine,” Klopp said post-match.

“I said last night that Diogo got a knock – that swelled up slightly directly after the game, obviously while I was in the press conference,” he added on Thursday.

Bridgerton fans: don’t miss this immersive Secret Cinema experience

“Diogo, good chance he will be alright but we need to have a closer look tomorrow. That’s it.”

Liverpool made seven changes for the midweek match, allowing Virgil van Dijk, Trent Alexander-Arnold and Andrew Robertson a full rest while Sadio Mane, Thiago Alcantara and Fabinho were given only a runout off the bench.

Roberto Firmino’s brace makes him a candidate to start at Wembley as Klopp formulates his attack to face City for the second time in a week.

It remains to be seen if Caoimhin Kelleher will be entrusted with the gloves as Liverpool’s cup goalkeeper, or if usual No1 Alisson will return for such a huge game.

 *Predicted Man City XI* (4-3-3): Steffen; Cancelo, Stones, Laporte, Ake; Silva, Rodri, Gundogan; Mahrez, Sterling, Grealish.

*Predicted Liverpool XI* (4-3-3): Kelleher; Alexander-Arnold, Matip, Van Dijk, Robertson; Henderson, Fabinho, Thiago; Salah, Jota, Mane.