Portugal has released a 26-man squad that will face the Super Eagles in a friendly in Lisbon on November 17.
The squad will also feature at the 2022 FIFA World Cup in Qatar.
Talismanic captain Cristiano Ronaldo headlines the squad, with key stars like Bruno Fernandes, Bernardo Silva, Rafael Leao, and Joao Felix also included.
Veteran defender, Pepe, Manchester City duo, Ruben Dias and Joao Cancelo are also part of the team.
It will be the first ever meeting between Portugal and Nigeria at the senior level.
The Super Eagles' head coach, Jose Peseiro, has yet to release his roster for the friendly.
Portugal will face Ghana, Uruguay, and South Korea in Group H at the World Cup.
Nigeria failed to qualify for the global soccer fiesta after losing to Ghana in the playoff.